Time
\n22 April 2020, 13:00<\/p>\n
Place<\/p>\n
Digital defence:
\nhttps:\/\/ucph-ku.zoom.us\/webinar\/register\/WN_yPmqEjyfSD2CIgM-27ksxQ. Webinar ID: 641-315-430<\/p>\n
Instructions: To attend the PhD defence, follow the link and hereafter the instructions to download the required Zoom-client. If the Zoom-client is incompatible with your pc, smartphone etc., or if you are affiliated to Region H, you can attend via an Internet browser (use Google Chrome). Log-in in due time.<\/p>\n
Opponents
\nProfessor Inge Tetens .(chair), Department of Nutrition, Exercise and Sports, University of Copenhagen, Denmark.<\/p>\n
Professor Thomas Nystr\u00f6m, Karolinska Instituttet, Sweden.<\/p>\n
Professor and chief consultant Jens Meldgaard Bruun, Steno Diabetes Center Aarhus, Aarhus University Hospital, University of Aarhus, Denmark.<\/p>\n
Main supervisor
\nAssociate professor, Thomas Meinert Larsen, Department of Nutrition, Exercise and Sports, University of Copenhagen, Denmark.<\/p>\n
Primary co-supervisor
\nProfessor, DMSc Jens Juul Holst, University of Copenhagen, Novo Nordisk Foundation Center for Basic Metabolic Research, Denmark<\/p>\n
Co-supervisors
\nDMSc Thure Krarup, Copenhagen University Hospital Bispebjerg, Department of Endocrinology, Denmark<\/p>\n
Professor, DMSc Steen Bendix Haugaard, Copenhagen University Hospital Bispebjerg, Department of Endocrinology, Denmark<\/p>\n
Professor, DMSc Arne Astrup, University of Copenhagen, Department of Nutrition, Exercise and Sports, Denmark<\/p>\n
Professor, DMSc Sten Madsbad, Copenhagen University Hospital Hvidovre, Department of Endocrinology, Denmark.<\/p>\n
About the thesis
\nNutritional therapy is recognized as a first-line therapeutic intervention in patients with type 2 diabetes. However, dietary recommendations are ambiguous and no clear consensus exists regarding the macronutrient distribution of the diabetes diet.<\/p>\n
Current Danish diabetes dietary guidelines recommend a macronutrient distribution of 45-60 energy percent (E%) from carbohydrates, 10-20 E% from protein and <35 E% from fat. The American diabetes association has recently recommended carbohydrate-restriction as one out of several viable nutritional therapeutic interventions.<\/p>\n
Although meta-analyses have revealed receding or absent long-term effects, it has been suggested that carbohydrate-restriction may improve glycemic control. Nevertheless, evaluation of dietary interventions remains complex as most feeding studies are influenced by a concomitant weight loss affecting the metabolic outcomes.<\/p>\n
This PhD project aimed to investigate the effects of a conventional diabetes diet (carbohydrates\/proteins\/fat; 50\/17\/33 E%) and an iso-energetic carbohydrate-reduced high-protein diet (carbohydrates\/proteins\/fat; 30\/30\/40 E%) during 6 weeks of full meal provision aiming at weight stability in patients with type 2 diabetes.<\/p>\n