The active principle in a mushroom found in Denmark is particularly poisonous to cancer cells. This is according to research at the Faculty of Pharmaceutical Sciences, University of Copenhagen, as reported by HealthCanal.com and other health science media. <\/p>\n
It was Dr. Ming Chen, a Chinese\u2013Danish physician at S\u00f8nderborg hospital and specialist in Chinese folk medicine, who made the first discovery. Now scientists at the faculty hope to synthesise and refine substances in the mushroom for future drug development. <\/p>\n
\u00bbThe Faculty of Pharmaceutical Sciences has investigated the mushroom\u2019s chemistry and, based on the substances isolated from it, we are developing a refined chemical compound that is even more effective and selective,\u00ab says S\u00f8ren Br\u00f8gger Christensen, Professor of Natural Products Research at the Faculty of Pharmaceutical Sciences. <\/p>\n
He explains to the University Post that the exact type of mushroom is being withheld due to an ongoing patent application process.<\/p>\n
\u00bbWe don’t want to exclude ourselves from any possibilities of gaining patent beforehand,\u00ab he says. <\/p>\n
The project has received DKK 2.6 million in financial support from Protech Investment Ltd \u2013 a spin-off from a large Chinese producer of natural medicines.<\/p>\n
Many substances found in fungi are registered as drugs to support chemotherapy treatments for cancer, HealthCanal.com reports.<\/p>\n
Among others, the mushroom Lentinula edodes, commonly known as Shiitake, is the primary ingredient in a registered drug extract on the Japanese market.<\/p>\n
In Denmark, mushrooms have primarily been used in food preparation, while some species have been used as intoxicants. <\/p>\n
At the Faculty of Pharmaceutical Sciences, it was exchange student Xuemei Liu, also from China, who isolated the active principles.<\/p>\n
\u00bbThis is a completely new class of natural compounds, which makes the research results unique,\u00ab explains Christensen, who has been collaborating with Chen since 1990.<\/p>\n
He emphasises that, as with all new drugs, using the results to develop a viable product will be a long, difficult process. <\/p>\n
miy@adm.ku.dk<\/p>\n