DanStem Seminar by Daniel St. Johnston

Daniel St. Johnston, The Gurdon Institute, University of Cambridge

Title: Multiple modes of epithelial polarity

Cell polarity is essential for normal cell function and for several key developmental processes, such as cell migration, axis determination and asymmetric stem cell divisions, whereas loss of polarity is a critical step in the formation of tumours. The group using Drosophila, mouse intestinal organoids and mammalian tissue culture cells to analyse how polarity arises and how cortical polarity factors regulate other polarised aspects of cell behaviour.

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