Københavns Universitet
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DanStem Seminar by Hans Schöler


Seminar — The DanStem Seminar Series focus on topics within stem cell and developmental biology. It features Internationally renowned scientists and is organized and coordinated by DanStem's Principal Investigator Professor Anne Grapin-Botton, DanStem.


Date & Time:

CPR Seminar room Panum Building 6, 2nd floor

Hosted by:
The Danish Stem Cell Center, DanStem


Title: Induction of Multi- and Pluripotent Stem Cells


How does pluripotency develop and what are the mechanisms that drive this process? Hans Schöler and his team have made good progress in answering this question. The researchers have shown that a gene called Oct4 plays a key role. Normally, it is only expressed in two types of cells, which are completely undeveloped: embryonic stem cells and precursors of egg and sperm cells (gametes). By contrast, in all mature cells, Oct4 is in a Sleeping Beauty−like state. If we want to transform mature cells into pluripotent cells, Oct4 must be targeted and activated.

All are welcome. Registration is not needed.