Is appetite reduction an effective tool for body weight management in the context of obesity?

Time

22 October 2019, 13:00

Place

Festauditoriet (aud. A1-01.01), Bülowsvej 17, 1870 Frederiksberg C

Opponents

Professor Susanne Bügel (chair), Department of Nutrition, Exercise and Sports, University of Copenhagen, Denmark.

Professor Emerita Barbara Livingstone, Biomedical Science Research Institute, Ulster University, Ireland.

Professor Emeritus Stephan Rössner, Department of Medicine University of Karolinska, Sweden.

Supervisor

Professor Anders Sjödin, Department of Nutrition, Exercise and Sports, University of Copenhagen, Denmark.

Co-supervisor

Professor Arne Astrup, Department of Nutrition, Exercise and Sports, University of Copenhagen, Denmark.

About the thesis

Intentional weight loss activates several physiological mechanisms including stimulation of signalling molecules that increase appetite. Because appetite plays an important role in the individual’s ability to control energy intake, the upregulation of these mechanisms makes further weight loss as well as weight loss maintenance a real challenge. New dietary based concepts where appetite can be satisfied with less energy may be an option to help people manage body weight in order to maintain health and wellbeing throughout life. However, as the reasons for eating are highly multifactorial, it cannot be taken for granted that reduction in appetite improves body weight management.

Based on a systematic review and meta-analysis as well as results from the SATIN study, the relationship between appetite and body weight management was investigated. Results from acute appetite tests (the STABLE and the SLIM8 studies) were additionally used to investigate different concepts for manipulating appetite.

Read more: https://nexs.ku.dk/english/calendar/2019/phd_thea-toft-hansen/