Precision medicine Bubble - August Krogh Club seminar

August Krogh Club seminar

Time

13 November 2018

14:00-15:00: Seminar and discussion
15:00-16:00: Post seminar servings and socializing

Abstract

In “Precision Medicine Bubble” I will present a skeptical view of the Precision Medicine (PM) paradigm. To do this I will deconstruct a key figure in one of the foundational documents of the PM movement, the 1999 Shattuck Lecture by Francis Collins Published in the New England Journal of Medicine.

I will then review progress to date on the key nodes in the figure and ask “How is it going so far?”.

I will close by suggesting how biomedical research might recover from the current genome-mania.

Publications

Joyner MJ, Paneth N: Seven Questions for Personalized Medicine. JAMA. 2015 Sep 8;314(10):999-1000.

Joyner MJ: Precision Medicine, Cardiovascular Disease and Hunting Elephants. Prog Cardiovasc Dis. 2016 May-Jun;58(6):651-60. Epub 2016 Feb 21.

Collins FS: Shattuck lecture–medical and societal consequences of the Human Genome Project. N Engl J Med. 1999 Jul 1;341(1):28-37.

Research profile

Michael J. Joyner, M.D., is the Caywood Professor of Anesthesiology at Mayo Clinic where he was named Distinguished Investigator in 2010.  His research focuses on exercise physiology, human performance, blood pressure regulation, metabolism, and transfusion practices.

He is also interested in the limits of scientific reductionism and the de-hyping of biomedical communications. The latter interest has led to a number of thought provoking and critical essays on the so-called Precision Medicine narrative in the popular press and key scientific journals.

Professor Joyner attended the University of Arizona where he graduated with a B.S. in 1981 and an M.D. in 1987.  After leaving Arizona he completed his residency training in anesthesiology at the Mayo Clinic in 1993 and then developed an independent research laboratory that has been funded by NIH since that time.

His former fellows have established research programs at leading institutions throughout the world and he has held leadership positions at Mayo, in the extramural research community, and with leading journals.

Read more: https://akc.ku.dk/calendar/2018/michael-joyner_seminar/